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Research & Innovation

Clinical Trials
Phase II to Phase IV

At GHCT, we are at the forefront of clinical research — connecting Miami patients to groundbreaking treatments and contributing to the global advancement of medicine.

Understanding the Process

The Three Phases of Research

Each phase of a clinical trial serves a distinct purpose in the journey from laboratory discovery to approved treatment. GHCT conducts trials across all three phases.

Phase II

Efficacy & Safety Testing

Phase II trials evaluate whether a new treatment works as intended and continue to assess its safety. Participants are closely monitored as researchers refine dosing and identify potential side effects.

  • Typically involves 100–300 participants
  • Evaluates treatment effectiveness
  • Monitors short-term side effects
  • Refines dosing protocols
  • Builds evidence for Phase III advancement
Phase III

Large-Scale Confirmation

Phase III trials confirm effectiveness, monitor adverse reactions, and compare the new treatment to existing standard-of-care options. These large-scale studies form the basis for regulatory approval.

  • Involves 1,000–3,000+ participants
  • Randomized controlled trial design
  • Compares to existing treatments
  • Provides data for FDA/regulatory review
  • Multi-site, often international coordination
Phase IV

Post-Market Surveillance

Phase IV studies occur after a treatment has been approved and is on the market. They gather long-term safety data, identify rare side effects, and explore new uses for approved therapies.

  • Conducted after regulatory approval
  • Long-term safety and effectiveness monitoring
  • Identifies rare or delayed adverse events
  • Explores additional indications
  • Supports real-world evidence generation

Currently Enrolling

Active Clinical Trials

Miami Climate & Health Trial

EnrollingPhase III

Investigating the impact of climate change on chronic disease outcomes in South Florida populations.

Inquire About This Trial

Cardiovascular Risk Reduction Study

EnrollingPhase II

Evaluating a novel intervention to reduce cardiovascular risk factors in high-risk adults.

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Metabolic Syndrome Management Trial

EnrollingPhase III

Testing a comprehensive lifestyle and pharmacological approach to metabolic syndrome.

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Hypertension Control Study

EnrollingPhase IV

Post-market surveillance of an approved antihypertensive in diverse Miami patient populations.

Inquire About This Trial

Participant Benefits

Why Participate in a GHCT Trial?

Access Cutting-Edge Treatments

Gain access to promising therapies before they are widely available to the public.

Close Medical Monitoring

Receive frequent check-ups and attentive care from our experienced research team throughout the trial.

Compensation for Your Time

Many of our trials offer financial compensation for participants' time and travel.

Advance Global Medicine

Your participation directly contributes to medical breakthroughs that benefit patients worldwide.

Expert Research Team

Our board-certified physicians and research coordinators guide you safely through every step.

No Cost for Trial-Related Care

Study-related medical exams, lab work, and investigational treatments are provided at no cost.

"Addressing the critical link between health and climate change — one trial at a time."

GHCT's Miami trial is part of a global effort to understand how environmental factors shape human health outcomes across diverse populations.

Join a Clinical Trial